BDBM328630 (1S,2R)-2- (trifluoromethyl)cyclohexyl ((S)-2- (acetamidomethyl)-4-((4- fluorophenyl)sulfonyl)-3,4- dihydro-2H-benzo[b][1,4]oxazin- 6-yl)carbamate::US9663502, 27i
SMILES CC(=O)NC[C@H]1CN(c2cc(NC(=O)O[C@H]3CCCC[C@H]3C(F)(F)F)ccc2O1)S(=O)(=O)c1ccc(F)cc1
InChI Key InChIKey=LWHGLBCNRRNDQF-DWLFOUALSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 328630
Affinity DataIC50: 3.77nMAssay Description:The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., a biochemical TR-FRET assay....More data for this Ligand-Target Pair