BDBM328637 (S)-1,1,1-trifluoro-3,3- dimethylbutan-2-yl ((S)-2- (acetamidomethyl)-4-((4- fluorophenyl)sulfonyl)-3,4-dihydro- 2H-benzo[b][1,4]oxazin-6- yl)carbamate::US9663502, 29F

SMILES CC(=O)NC[C@H]1CN(c2cc(NC(=O)O[C@@H](C(C)(C)C)C(F)(F)F)ccc2O1)S(=O)(=O)c1ccc(F)cc1

InChI Key InChIKey=CNEVWLMGIZPXLK-UWJYYQICSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 328637   

TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Lycera

US Patent
LigandPNGBDBM328637((S)-1,1,1-trifluoro-3,3- dimethylbutan-2-yl ((S)-2...)
Affinity DataIC50:  2.77nMAssay Description:The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., a biochemical TR-FRET assay....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent