BDBM329074 4-(5-bromo-6-(2,4-dichloro-6- methylphenoxy)-3-pyridinyl)- 2,5-difluoro-N- (methylsulfonyl)benzamide::4-(5-bromo-6-(2,4-dichloro-6-methylphenoxy)-3-pyridinyl)-2,5-difluoro-N-(methylsulfonyl)benzamide::US9663508, Example 575

SMILES Cc1cc(Cl)cc(Cl)c1Oc1ncc(cc1Br)-c1cc(F)c(cc1F)C(=O)NS(C)(=O)=O

InChI Key InChIKey=DWODLVKNUHVYSP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 329074   

TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM329074(4-(5-bromo-6-(2,4-dichloro-6- methylphenoxy)-3-pyr...)
Affinity DataIC50: >4.90E+3nMAssay Description:293 cells stably transfected with human Nav 1.5 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology syste...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM329074(4-(5-bromo-6-(2,4-dichloro-6- methylphenoxy)-3-pyr...)
Affinity DataIC50:  42.4nMAssay Description:HEK 293 cells stably transfected with human Nav1.7 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology sy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent