BDBM329088 5-chloro-4-(5-chloro-6-(2,3,5-trifluorophenoxy)-3-pyridinyl)-::5-chloro-4-(5-chloro-6-(2,3,5-trifluorophenoxy)-3-pyridinyl)-2-fluoro-N-(methylsulfonyl)benzamide::US9663508, Example 589

SMILES CS(=O)(=O)NC(=O)c1cc(Cl)c(cc1F)-c1cnc(Oc2cc(F)cc(F)c2F)c(Cl)c1

InChI Key InChIKey=JMYYWBZZOVENRM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 329088   

TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM329088(5-chloro-4-(5-chloro-6-(2,3,5-trifluorophenoxy)-3-...)
Affinity DataIC50: >3.00E+3nMAssay Description:293 cells stably transfected with human Nav 1.5 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology syste...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM329088(5-chloro-4-(5-chloro-6-(2,3,5-trifluorophenoxy)-3-...)
Affinity DataIC50:  49.9nMAssay Description:HEK 293 cells stably transfected with human Nav1.7 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology sy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent