BDBM329122 4-(5-Chloro-6-(3-Fluoro-4-Methylphenoxy)Pyridin-3-yl)-2-Fluoro-5-Methyl-N-(Methylsulfonyl)Benzamide::4-(5-chloro-6-(3-fluoro-4-methylphenoxy)-3-pyridinyl)-2-fluoro-5-methyl-N-(methylsulfonyl)benzamide::US9663508, Example 623

SMILES Cc1ccc(Oc2ncc(cc2Cl)-c2cc(F)c(cc2C)C(=O)NS(C)(=O)=O)cc1F

InChI Key InChIKey=UKRLRECBBHMSJK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 329122   

TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM329122(4-(5-Chloro-6-(3-Fluoro-4-Methylphenoxy)Pyridin-3-...)
Affinity DataIC50:  4.84E+3nMAssay Description:293 cells stably transfected with human Nav 1.5 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology syste...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM329122(4-(5-Chloro-6-(3-Fluoro-4-Methylphenoxy)Pyridin-3-...)
Affinity DataIC50:  48.5nMAssay Description:HEK 293 cells stably transfected with human Nav1.7 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology sy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent