BDBM329146 4-(6-((1R)-1-(1,3-benzothiazol-2-yl)ethoxy)-5-chloro-3-pyridinyl)-2-fluoro-5-methyl-N-(methylsulfonyl)benzamide::Mixture of 4-(6-((1R)-1-(1,3- benzothiazol-2-yl)ethoxy)-5- chloro-3-pyridinyl)-2-fluoro-5- methyl-N- (methylsulfonyl)benzamide and 4-(6-((1S)-1-(1,3-benzothiazol- 2-yl)ethoxy)-5-chloro-3- pyridinyl)-2-fluoro-5-methyl- N-(methylsulfonyl)benzamide::US9663508, Example 647::US9663508, Example 709
SMILES C[C@@H](Oc1ncc(cc1Cl)-c1cc(F)c(cc1C)C(=O)NS(C)(=O)=O)c1nc2ccccc2s1
InChI Key InChIKey=QHNDRICPFGSWQW-CYBMUJFWSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 329146
Affinity DataIC50: 76nMAssay Description:HEK 293 cells stably transfected with human Nav1.7 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology sy...More data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+3nMAssay Description:293 cells stably transfected with human Nav 1.5 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology syste...More data for this Ligand-Target Pair
Affinity DataIC50: 34.9nMAssay Description:HEK 293 cells stably transfected with human Nav1.7 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology sy...More data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+3nMAssay Description:293 cells stably transfected with human Nav 1.5 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology syste...More data for this Ligand-Target Pair