BDBM329187 4-(5-cyano-6-(2,4-dichloro-6- methylphenoxy)-3-pyridinyl)-3- methoxy-N- (methylsulfonyl)benzamide::4-(5-cyano-6-(2,4-dichloro-6-methylphenoxy)-3-pyridinyl)-3-methoxy-N-(methylsulfonyl)benzamide::US9663508, Example 689

SMILES COc1cc(ccc1-c1cnc(Oc2c(C)cc(Cl)cc2Cl)c(c1)C#N)C(=O)NS(C)(=O)=O

InChI Key InChIKey=ULKCBFMHTCGKKY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 329187   

TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM329187(4-(5-cyano-6-(2,4-dichloro-6- methylphenoxy)-3-pyr...)
Affinity DataIC50:  1.00E+3nMAssay Description:293 cells stably transfected with human Nav 1.5 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology syste...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM329187(4-(5-cyano-6-(2,4-dichloro-6- methylphenoxy)-3-pyr...)
Affinity DataIC50:  28.4nMAssay Description:HEK 293 cells stably transfected with human Nav1.7 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology sy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent