BDBM329229 4-(5-chloro-6-((1R)-1-cyclobutylethoxy)-3-pyridinyl)-2-fluoro-5-methoxy-N-(methylsulfonyl)benzamide::Mixture of 4-(5-chloro-6-((1S)- 1-cyclobutylethoxy)-3- pyridinyl)-2-fluoro-5-methoxy- N-(methylsulfonyl)benzamide and 4-(5-chloro-6-((1R)-1- cyclobutylethoxy)-3-pyridinyl)- 2-fluoro-5-methoxy-N- (methylsulfonyl)benzamide::US9663508, Example 719::US9663508, Example 769

SMILES COc1cc(C(=O)NS(C)(=O)=O)c(F)cc1-c1cnc(O[C@H](C)C2CCC2)c(Cl)c1

InChI Key InChIKey=BIEXPGXIOPWBIA-LLVKDONJSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 329229   

TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM329229(4-(5-chloro-6-((1R)-1-cyclobutylethoxy)-3-pyridiny...)
Affinity DataIC50:  50nMAssay Description:HEK 293 cells stably transfected with human Nav1.7 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology sy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM329229(4-(5-chloro-6-((1R)-1-cyclobutylethoxy)-3-pyridiny...)
Affinity DataIC50:  89nMAssay Description:HEK 293 cells stably transfected with human Nav1.7 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology sy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent