BDBM329287 4-(5-chloro-6-(2,4-dichloro-6- methylphenoxy)-3-pyridinyl)- N-(ethylsulfonyl)-3- methoxybenzamide::4-(5-chloro-6-(2,4-dichloro-6-methylphenoxy)-3-pyridinyl)-N-(ethylsulfonyl)-3-methoxybenzamide::US9663508, Example 788

SMILES CCS(=O)(=O)NC(=O)c1ccc(c(OC)c1)-c1cnc(Oc2c(C)cc(Cl)cc2Cl)c(Cl)c1

InChI Key InChIKey=MLRCOMSZIJSMGF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 329287   

TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM329287(4-(5-chloro-6-(2,4-dichloro-6- methylphenoxy)-3-py...)
Affinity DataIC50:  1.38E+3nMAssay Description:293 cells stably transfected with human Nav 1.5 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology syste...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM329287(4-(5-chloro-6-(2,4-dichloro-6- methylphenoxy)-3-py...)
Affinity DataIC50:  24.8nMAssay Description:HEK 293 cells stably transfected with human Nav1.7 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology sy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent