BDBM329298 4-(5-chloro-6-(2,4-dichloro-6- methylphenoxy)-3-pyridinyl)-2- fluoro-5-methyl-N-(1,3-thiazol- 2-ylsulfonyl)benzamide::4-(5-chloro-6-(2,4-dichloro-6-methylphenoxy)-3-pyridinyl)-2-fluoro-5-methyl-N-(1,3-thiazol-2-ylsulfonyl)benzamide::US9663508, Example 799

SMILES Cc1cc(Cl)cc(Cl)c1Oc1ncc(cc1Cl)-c1cc(F)c(cc1C)C(=O)NS(=O)(=O)c1nccs1

InChI Key InChIKey=YTFBGOIIROWIRX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 329298   

TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM329298(4-(5-chloro-6-(2,4-dichloro-6- methylphenoxy)-3-py...)
Affinity DataIC50:  669nMAssay Description:293 cells stably transfected with human Nav 1.5 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology syste...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM329298(4-(5-chloro-6-(2,4-dichloro-6- methylphenoxy)-3-py...)
Affinity DataIC50:  23.1nMAssay Description:HEK 293 cells stably transfected with human Nav1.7 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology sy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent