BDBM329730 (3S,4R)-1-(1-(2-chloro-6-cyclopropylbenzoyl)-4-fluoro-1H-indazol-3-yl)-3-hydroxy-4-methylpiperidine-4-carboxylic acid::US9663522, 9B

SMILES C[C@]1(CCN(C[C@H]1O)c1nn(C(=O)c2c(Cl)cccc2C2CC2)c2cccc(F)c12)C(O)=O

InChI Key InChIKey=DXBRGPBHJUIWHM-HOYKHHGWSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 329730   

TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM329730((3S,4R)-1-(1-(2-chloro-6-cyclopropylbenzoyl)-4-flu...)
Affinity DataIC50:  78nMAssay Description:The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent