BDBM329740 Preparation of (−)-2-[(4R)-6-(4-chlorophenyl)-1-methyl-4H-[1,2,4]triazolo[4,3-a][1]benzazepin-4-yl]-1-(2-oxa-6-azaspiro[3.3]hept-6-yl)ethanone::US9663523, Example 4

SMILES Cc1nnc2[C@@H](CC(=O)N3CC4(COC4)C3)C=C(c3ccc(Cl)cc3)c3ccccc3-n12

InChI Key InChIKey=JQYSUMDNNSPXEQ-GOSISDBHSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 329740   

TargetBromodomain-containing protein 4(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM329740(Preparation of (−)-2-[(4R)-6-(4-chlorophenyl...)
Affinity DataIC50:  130nMAssay Description:For this purpose, a time-resolved fluorescence resonance energy transfer (TR-FRET) assay was used, which measures the binding between N-terminally Hi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent