BDBM330401 (S)N6-(1-acryloylazetidin-3-yl)-N4-(3-chloro-4-fluorophenyl)-7-(tetrahydrofuran-3-yloxy)quinazoline-4,6-diamine::US9725439, 3
SMILES Fc1ccc(Nc2ncnc3cc(O[C@H]4CCOC4)c(NC4CN(C4)C(=O)C=C)cc23)cc1Cl
InChI Key InChIKey=RSWAKAGASMNZDR-INIZCTEOSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 330401
TargetEpidermal growth factor receptor [T790M,L858R](Homo sapiens (Human))
Chia Tai Tianqing Pharmaceutical Group
US Patent
Chia Tai Tianqing Pharmaceutical Group
US Patent
Affinity DataIC50: 0.600nMAssay Description:EGFR, EGFR (T790M, L858R), HER2 kinase were expressed and purified through an insect cell expression system by the Department of Biology, Centaurus B...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Chia Tai Tianqing Pharmaceutical Group
US Patent
Chia Tai Tianqing Pharmaceutical Group
US Patent
Affinity DataIC50: 0.200nMAssay Description:EGFR, EGFR (T790M, L858R), HER2 kinase were expressed and purified through an insect cell expression system by the Department of Biology, Centaurus B...More data for this Ligand-Target Pair