BDBM331651 Preparation of 5-(4-(2-((5-(tert-butyl)isoxazol-3-yl)amino)-2-oxoethyl)phenyl)-N-(1-methylpiperidin-4-yl)-1H-pyrrolo[2,3-b]pyridine-2-carboxamide::US9725465, Example 69

SMILES CN1CCC(CC1)NC(=O)c1cc2cc(cnc2[nH]1)-c1ccc(CC(=O)Nc2cc(on2)C(C)(C)C)cc1

InChI Key InChIKey=PPWJSGJXDDQXSW-UHFFFAOYSA-N

Data  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 331651   

TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Ambit Biosciences

US Patent
LigandPNGBDBM331651(Preparation of 5-(4-(2-((5-(tert-butyl)isoxazol-3-...)
Affinity DataKd: <5nMAssay Description:Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Ambit Biosciences

US Patent
LigandPNGBDBM331651(Preparation of 5-(4-(2-((5-(tert-butyl)isoxazol-3-...)
Affinity DataKd: <5nMAssay Description:Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent