BDBM332084 4-[1-[5-(2-Fluorophenyl)-pyrimidin-2-yl]spiro[1,2-dihydro-indole-3,1'-cyclopropane]-6-carbonyl]-1-methyl-piperazin-2-one::US10189854, Compound 38

SMILES CN1CCN(CC1=O)C(=O)c1ccc2c(c1)N(CC21CC1)c1ncc(cn1)-c1ccccc1F

InChI Key InChIKey=LKZXYTDWBUVGMU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 332084   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Gruenenthal

US Patent
LigandPNGBDBM332084(4-[1-[5-(2-Fluorophenyl)-pyrimidin-2-yl]spiro[1,2-...)
Affinity DataIC50: <100nMAssay Description:The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent