BDBM332430 4-(4-chloro-1- (2-chloro-6- cyclopropyl- benzoyl)-1H- indazol-3-yl)- 3-fluoro benzoic acid::US10196354, Example 1Z::US9745265, 1Z
SMILES OC(=O)c1ccc(-c2nn(C(=O)c3c(Cl)cccc3C3CC3)c3cccc(Cl)c23)c(F)c1
InChI Key InChIKey=ALIZPFBIRRYJQJ-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 332430
Affinity DataIC50: 4nMAssay Description:To identify novel antagonists of RORgammaT, an assay was developed which employs the interaction of RORgammaT with its co-activator peptide SRC1_2. T...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I...More data for this Ligand-Target Pair