BDBM33293 phenylpropanoic acid derivative, 17i::racemic

SMILES Cc1oc(nc1CCCc1ccc(CC(C(O)=O)n2nccn2)cc1)-c1ccccc1

InChI Key InChIKey=MBNINRCJDJMURD-UHFFFAOYSA-N

Data  2 IC50  2 EC50

PDB links: 1 PDB ID matches this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 33293   

TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Pfizer

LigandBDBM33293(phenylpropanoic acid derivative, 17i | racemic)Copy SMILESCopy InChI

Affinity DataIC50:  5nM EC50:  15nMpH: 7.4 T: 2°CAssay Description:Human 6His-PPAR ligand-binding domain was added to the mixture containing radioligand and test compound, followed by yttrium silicate polylysine SPA ...More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMedPDB3D Structure (crystal)
Copy BDB DOI

TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Pfizer

LigandBDBM33293(phenylpropanoic acid derivative, 17i | racemic)Copy SMILESCopy InChI

Affinity DataIC50:  24nM EC50:  182nMpH: 7.2 T: 2°CAssay Description:Human PPAR alpha receptor was expressed as recombinant glutathione-S-transferase (GST)-fusion proteins in Escherichia coli. The purified GST-hPPAR al...More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI