BDBM333197 US10196436, Compound 47

SMILES COc1cc(OC)c(Cl)c(c1Cl)-c1cc(OC)c2nc(Nc3c(F)cccc3NC(=O)C=C)ncc2c1

InChI Key InChIKey=SYYYGOHNLIGMIE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 333197   

TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Blueprint Medicines

US Patent
LigandPNGBDBM333197(US10196436, Compound 47)
Affinity DataIC50:  55nMAssay Description:In each well of a 384-well plate, 0.1 ng/ul of wild type FGFR-1 (Carna Biosciences, Inc.) was incubated in a total of 12.5 ul of buffer (100 mM HEPES...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
Blueprint Medicines

US Patent
LigandPNGBDBM333197(US10196436, Compound 47)
Affinity DataIC50: <10nMAssay Description:In each well of a 384-well plate, 0.5 ng/ul of wild type FGFR-4 (Carna Biosciences, Inc.) was incubated in a total of 12.5 ul of buffer (100 mM HEPES...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent