BDBM333217 (2S,3R,4S)-2-(8-((3-methylbenzyl)amino)-[1,2,4]triazolo[4,3-a]pyrazin-3-yl)tetrahydrothiophene-3,4-diol::US10196396, Compound 12

SMILES Cc1cccc(CNc2nccn3c(nnc23)[C@@H]2SC[C@@H](O)[C@H]2O)c1

InChI Key InChIKey=FAPJRNUDQYPEPM-MGPQQGTHSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 333217   

TargetAdenosine receptor A3(Homo sapiens (Human))
Handok

US Patent
LigandPNGBDBM333217((2S,3R,4S)-2-(8-((3-methylbenzyl)amino)-[1,2,4]tri...)
Affinity DataKi:  55nMAssay Description:HEK-293 cell membrane homogenates (32 μg protein), in which A3 adenosine receptors were expressed, are incubated for 120 min at 22° C. with 0.15...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine receptor A3(Homo sapiens (Human))
Handok

US Patent
LigandPNGBDBM333217((2S,3R,4S)-2-(8-((3-methylbenzyl)amino)-[1,2,4]tri...)
Affinity DataIC50:  550nMAssay Description:HEK-293 cell membrane homogenates (32 μg protein), in which A3 adenosine receptors were expressed, are incubated for 120 min at 22° C. with 0.15...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent