BDBM333406 6-(2,4-Difluorophenoxy)-1-methyl-5-(6-methyl-7-oxo-6,7-dihydro-1H-pyrrolo[2,3-c]pyridin-4-yl)-1,3-dihydro-2H-benzimidazol-2-one::US9737516, Example 2

SMILES Cn1c2cc(Oc3ccc(F)cc3F)c(cc2[nH]c1=O)-c1cn(C)c(=O)c2[nH]ccc12

InChI Key InChIKey=HHKRXYVZJMMYBO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 333406   

TargetBromodomain-containing protein 4 [368-440](Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM333406(6-(2,4-Difluorophenoxy)-1-methyl-5-(6-methyl-7-oxo...)
Affinity DataIC50: <100nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for BD2. Inhib...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [75-147](Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM333406(6-(2,4-Difluorophenoxy)-1-methyl-5-(6-methyl-7-oxo...)
Affinity DataIC50: <100nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for BD2. Inhib...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent