BDBM333654 1-(3-(6- Methoxy-7- (2- methoxyethoxy) quinazolin-4- yloxy)phenyl)- 3-(5- phenylisoxazol- 3-yl) urea::US9730937, Example 203
SMILES COCCOc1cc2ncnc(Sc3cccc(NC(=O)Nc4cc(on4)-c4ccccc4)c3)c2cc1OC
InChI Key InChIKey=RMRSIWFQLVGXFF-UHFFFAOYSA-N
Data 3 Kd
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 333654
Affinity DataKd: >1.00E+3nMAssay Description:Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336....More data for this Ligand-Target Pair
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Ambit Biosciences
US Patent
Ambit Biosciences
US Patent
Affinity DataKd: >1.00E+3nMAssay Description:Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336....More data for this Ligand-Target Pair
Affinity DataKd: >1.00E+3nMAssay Description:Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336....More data for this Ligand-Target Pair