BDBM333707 1-(3-(2- fluoropropan-2- yl)isoxazol-5- yl)-3-(3-(7- hydroxy-6- methoxy- quinazolin- 4-yloxy) phenyl)urea::US9730937, Example 257
SMILES COc1cc2c(Oc3cccc(NC(=O)Nc4cc(no4)C(C)(C)F)c3)ncnc2cc1O
InChI Key InChIKey=QTEHHMZLVUOFOS-UHFFFAOYSA-N
Data 3 Kd
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 333707
Affinity DataKd: <250nMAssay Description:Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336....More data for this Ligand-Target Pair
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Ambit Biosciences
US Patent
Ambit Biosciences
US Patent
Affinity DataKd: <250nMAssay Description:Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336....More data for this Ligand-Target Pair
Affinity DataKd: <250nMAssay Description:Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336....More data for this Ligand-Target Pair