BDBM335734 US9738640, Example 7

SMILES Fc1ccc(cc1Cl)C(=O)Nc1cc2cc[nH]c2cn1

InChI Key InChIKey=XPSVDJCQOLKLRJ-UHFFFAOYSA-N

Data  1 KI  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 335734   

TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Ntz Lab

Curated by ChEMBL
LigandPNGBDBM335734(US9738640, Example 7)
Affinity DataKi:  32nMAssay Description:Inhibition of human recombinant MAO-B expressed in baculovirus infected BTI-TN-5B1-4 insect cells using p-tyramine as substrate preincubated for 15 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Ntz Lab

Curated by ChEMBL
LigandPNGBDBM335734(US9738640, Example 7)
Affinity DataIC50:  72nMAssay Description:Recombinant human MAO-B enzyme, expressed in baculovirus-infected insect cells, was purchased from Sigma-Aldrich (M7441). The assay was performed as ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Ntz Lab

Curated by ChEMBL
LigandPNGBDBM335734(US9738640, Example 7)
Affinity DataIC50:  72nMAssay Description:Inhibition of human recombinant MAO-B expressed in baculovirus infected BTI-TN-5B1-4 insect cells using p-tyramine as substrate preincubated for 15 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Rattus norvegicus (rat))
Ntz Lab

Curated by ChEMBL
LigandPNGBDBM335734(US9738640, Example 7)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Sprague-Dawley rat liver MAO-A using p-tyramine as substrate preincubated for 15 mins and measured after 45 mins by resorufin-based flu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Ntz Lab

Curated by ChEMBL
LigandPNGBDBM335734(US9738640, Example 7)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant MAO-A expressed in baculovirus infected BTI-TN-5B1-4 insect cells using p-tyramine as substrate preincubated for 15 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Ntz Lab

Curated by ChEMBL
LigandPNGBDBM335734(US9738640, Example 7)
Affinity DataIC50: <1.00E+4nMAssay Description:Recombinant human MAO-A enzyme, expressed in baculovirus-infected insect cells, was purchased from Sigma-Aldrich (M7316). The assay was carried out i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAmine oxidase [flavin-containing] B(Rattus norvegicus (rat))
Ntz Lab

Curated by ChEMBL
LigandPNGBDBM335734(US9738640, Example 7)
Affinity DataIC50:  158nMAssay Description:Inhibition of Sprague-Dawley rat liver MAO-B using p-tyramine as substrate preincubated for 15 mins and measured after 45 mins by resorufin-based flu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed