BDBM336320 1-(7-chloro-5- (isoquinolin-4-yl) indolin-1- yl)ethanone::US9745282, 11

SMILES CC(=O)N1CCc2cc(cc(Cl)c12)-c1cncc2ccccc12

InChI Key InChIKey=RBJZBSIDQPWTGO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 336320   

TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM336320(1-(7-chloro-5- (isoquinolin-4-yl) indolin-1- yl)et...)
Affinity DataIC50:  60nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM336320(1-(7-chloro-5- (isoquinolin-4-yl) indolin-1- yl)et...)
Affinity DataIC50:  0.700nMAssay Description:V79 cell lines stably expressing the either the human CYP11B2 or the human CYP11B1 enzyme were generated using a standard transfection protocol. V79 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent