BDBM337292 (R)-3-(ethylamino)-6-(1-phenylethyl)-5,6-dihydro-1H-pyrazolo[4,3-g]quinazolin-7(8H)-one::US9745307, Example 29

SMILES CCNC(=N)c1cc2CN([C@H](C)c3ccccc3)C(=O)Nc2cc1N

InChI Key InChIKey=NSLKFHYYWCOTPL-GFCCVEGCSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 337292   

TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM337292((R)-3-(ethylamino)-6-(1-phenylethyl)-5,6-dihydro-1...)
Affinity DataIC50:  22nMAssay Description:Activated ERK2 activity was determined in an IMAP-FP assay (Molecular Devices). Using this assay format, the potency (IC50) of each compound was dete...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent