BDBM337635 6-Cyclohexyl-4-hydroxypyridazin-3(2H)-one::BDBM50431072::US9750748, 7

SMILES Oc1cc(n[nH]c1=O)C1CCCCC1

InChI Key InChIKey=VVTXBSWKKUAAHP-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 337635   

TargetD-amino-acid oxidase(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM337635(6-Cyclohexyl-4-hydroxypyridazin-3(2H)-one | BDBM50...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of human full length DAAO overexpressed in HEK293 cells after 30 mins by plate reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetD-amino-acid oxidase(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM337635(6-Cyclohexyl-4-hydroxypyridazin-3(2H)-one | BDBM50...)
Affinity DataIC50:  300nMAssay Description:Inhibition of human recombinant DAAO after 30 mins by plate reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetD-amino-acid oxidase(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM337635(6-Cyclohexyl-4-hydroxypyridazin-3(2H)-one | BDBM50...)
Affinity DataIC50:  1.10E+3nMAssay Description:The functional activity of compounds inhibiting the DAAO enzyme was determined by utilizing the co-product of the catalysis of D-Serine, H2O2, which ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD-amino-acid oxidase(Mus musculus)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM337635(6-Cyclohexyl-4-hydroxypyridazin-3(2H)-one | BDBM50...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of mouse full length DAAO overexpressed in HEK293 cells after 30 mins by plate reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetD-amino-acid oxidase(Rattus norvegicus (rat))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM337635(6-Cyclohexyl-4-hydroxypyridazin-3(2H)-one | BDBM50...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of rat full length DAAO overexpressed in HEK293 cells after 30 mins by plate reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed