BDBM338351 (3S,6R)-2-(2-fluoro-4-((1-(S- methylsulfonimidoyl)piperidin-4- yl)oxy)benzyl)-3-methyl-6-phenyl- 1,2-thiazinane 1,1-dioxide::US9751873, Example 38::US9751873, Example 39

SMILES C[C@H]1CC[C@H](c2ccccc2)S(=O)(=O)N1Cc1ccc(OC2CCN(CC2)S(C)(=N)=O)cc1F

InChI Key InChIKey=GLZDEPPOLPEWBJ-XZTGARFLSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 338351   

TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM338351((3S,6R)-2-(2-fluoro-4-((1-(S- methylsulfonimidoyl)...)
Affinity DataIC50:  17nMAssay Description:Assays were carried out in 16-microL reaction volumes in black 384 Plus F Proxiplates (Perkin-Elmer 6008269). All assay components except test ligand...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM338351((3S,6R)-2-(2-fluoro-4-((1-(S- methylsulfonimidoyl)...)
Affinity DataIC50:  150nMAssay Description:Assays were carried out in 16-microL reaction volumes in black 384 Plus F Proxiplates (Perkin-Elmer 6008269). All assay components except test ligand...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent