BDBM339278 US10201546, Example 136c
SMILES COc1nc2ccc(cc2c(Cl)c1C1CCCC1)[C@@](O)(c1cnnn1C)c1ccc(C)nc1C
InChI Key InChIKey=FXALQDYOXKYAHX-SANMLTNESA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 339278
Affinity DataKd: 1.40nMAssay Description:ThermoFluor is a fluorescence based assay that estimates ligand binding affinities by measuring the effect of a ligand on protein thermal stability (...More data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:A reporter assay was used to test functional activity of RORγt modulatory compounds on transcriptional activation driven by the RORγt LBD. ...More data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:For the RORγt construct used in the ThermoFluorŪ assay, numbering for the nucleotide sequences was based on the reference sequence for human ROR...More data for this Ligand-Target Pair