BDBM339942 6-fluoro-3-(6-(4- methylpiperazin-1-yl)pyridin- 3-yl)-1H-indole::US9758505, 10

SMILES CN1CCN(CC1)c1ccc(cn1)-c1c[nH]c2cc(F)ccc12

InChI Key InChIKey=VOHONPBZCYTMAD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 339942   

TargetTryptophan 2,3-dioxygenase(Homo sapiens (Human))
Iteos Therapeutics

US Patent
LigandPNGBDBM339942(6-fluoro-3-(6-(4- methylpiperazin-1-yl)pyridin- 3-...)
Affinity DataIC50:  720nMAssay Description:The compounds of formula I inhibit the enzymatic activity of human TDO2.To measure the TDO2 activity, the procedure described in Dolusic et al. J. Me...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent