BDBM340025 US9776988, Example 8

SMILES COc1cc(CCc2cc(n[nH]2)-c2nc3cc(ccc3[nH]2)C(=O)N2CCN(C)CC2)cc(OC)c1

InChI Key InChIKey=HIRADXZLYXUWGK-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 340025   

TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Celon Pharma

US Patent
LigandPNGBDBM340025(US9776988, Example 8)
Affinity DataIC50:  9.65nMAssay Description:The compounds were dissolved in 100% DMSO, and obtained solutions were serially diluted in reaction buffer (50 mM Tris pH 7.5, 10 mM MgCl2, 0.25 mM E...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Celon Pharma

US Patent
LigandPNGBDBM340025(US9776988, Example 8)
Affinity DataIC50:  79.3nMAssay Description:The compounds were dissolved in 100% DMSO, and obtained solutions were serially diluted in reaction buffer (50 mM Tris pH 7.5, 10 mM MgCl2, 0.25 mM E...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Celon Pharma

US Patent
LigandPNGBDBM340025(US9776988, Example 8)
Affinity DataIC50:  22.2nMAssay Description:The compounds were dissolved in 100% DMSO, and obtained solutions were serially diluted in reaction buffer (50 mM Tris pH 7.5, 10 mM MgCl2, 0.25 mM E...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Celon Pharma

US Patent
LigandPNGBDBM340025(US9776988, Example 8)
Affinity DataIC50:  2.13nMAssay Description:The compounds were dissolved in 100% DMSO, and obtained solutions were serially diluted in reaction buffer (50 mM Tris pH 7.5, 10 mM MgCl2, 0.25 mM E...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent