BDBM340823 US9765040, Compound 15

SMILES CC(C)n1c(nnc1C(C)(C)Oc1c(F)cc(F)cc1F)-c1ccc(cc1F)C(N)=O

InChI Key InChIKey=NZDMVTVSABUXKT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 340823   

Target11-beta-hydroxysteroid dehydrogenase 1(Rattus norvegicus (rat))
Astellas Pharma

US Patent
LigandPNGBDBM340823(US9765040, Compound 15)
Affinity DataIC50:  23nMAssay Description:The procedure for measuring the 11β-HSD1-inhibitory activity is as follows. The enzyme reaction and the measurement were carried out using a 384...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent