BDBM341347 N-(6-chloro-5-(2-(5-(4-chloro-2-fluorophenyl)-2-methyl-7,8-dihydro-[1,3,4]thiadiazolo[2',3':2,3]imidazo[4,5-c]pyridin-6(5H)-yl)-2-oxoethoxy)pyridin-2-yl)methanesulfonamide::US9765092, Example 1.4.39
SMILES Cc1nn2c3C(N(CCc3nc2s1)C(=O)COc1ccc(NS(C)(=O)=O)nc1Cl)c1ccc(Cl)cc1F
InChI Key InChIKey=WVDLBJODMXJEBA-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 341347
Affinity DataIC50: 5nMAssay Description:To generate the enzyme, full length human TPH1 is cloned into the plasmid pET20b(+) (Novagen) and expressed in E. coli. The bacterial cells are ruptu...More data for this Ligand-Target Pair