BDBM34150 4-(3-methyl-1H-indole-1-sulfonyl)aniline, 8::CHEMBL328816::N-arenesulfonylindole antagonist, 9
SMILES Cc1cn(c2ccccc12)S(=O)(=O)c1ccc(N)cc1
InChI Key InChIKey=ZNRJXSHXWJKTGJ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 34150
Affinity DataKi: 12nM ΔG°: -11.2kcal/mole EC50: 320nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed using membranes from HEK-293 transfected with human 5-HT6 receptor. In these membranes the receptor concent...More data for this Ligand-Target Pair
Affinity DataKi: 12nMpH: 7.4Assay Description:The h5-HT6 radioligand binding assays were performed as previously described. In brief, h5-HT6 cDNA was transiently expressed in HEK-293 cells using...More data for this Ligand-Target Pair
Affinity DataKi: 12nMAssay Description:Binding affinity against 5 Hydroxy tryptamine 6 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 12nMAssay Description:Binding affinity towards human 5-hydroxytryptamine 6 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 12nMAssay Description:Binding affinity towards human 5-hydroxytryptamine 6 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 13nMAssay Description:Binding affinity for human 5-hydroxytryptamine 6 receptorChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Antagonistic activity towards 5-hydroxytryptamine 6 receptor was evaluated in cAMP assayMore data for this Ligand-Target Pair