BDBM341648 6-chloro-5-(2-(5-(3-fluorothiophen-2-yl)-7,8-dihydro-thiazolo[2',3':2,3]imidazo[4,5-c]pyridin-6(5H)-yl)-2-oxoethoxy)-N,N-dimethylpicolinamide::US9765092, Example 6.8.2

SMILES CN(C)C(=O)c1ccc(OCC(=O)N2CCc3nc4sccn4c3C2c2sccc2F)c(Cl)n1

InChI Key InChIKey=KAYDRBVDKYSCQI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 341648   

TargetTryptophan 5-hydroxylase 1(Homo sapiens (Human))
Actelion Pharmaceuticals

US Patent
LigandPNGBDBM341648(6-chloro-5-(2-(5-(3-fluorothiophen-2-yl)-7,8-dihyd...)
Affinity DataIC50:  5nMAssay Description:To generate the enzyme, full length human TPH1 is cloned into the plasmid pET20b(+) (Novagen) and expressed in E. coli. The bacterial cells are ruptu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent