BDBM341654 2-(4-chloro-2-methylphenoxy)-1-(5-(2-fluoro-4-methyl-phenyl)-7,8-dihydrothiazolo[2',3':2,3]imidazo[4,5-c]-pyridin-6(5H)-yl)ethanone::US9765092, Example 6.10.1

SMILES Cc1ccc(C2N(CCc3nc4sccn4c23)C(=O)COc2ccc(Cl)cc2C)c(F)c1

InChI Key InChIKey=VUFITPLVHLCSDU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 341654   

TargetTryptophan 5-hydroxylase 1(Homo sapiens (Human))
Actelion Pharmaceuticals

US Patent
LigandPNGBDBM341654(2-(4-chloro-2-methylphenoxy)-1-(5-(2-fluoro-4-meth...)
Affinity DataIC50:  5nMAssay Description:To generate the enzyme, full length human TPH1 is cloned into the plasmid pET20b(+) (Novagen) and expressed in E. coli. The bacterial cells are ruptu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent