BDBM342149 1-((2-(tert-butyl)-4-(3-chlorophenyl)thiazol-5-yl)methyl)-3-(isoquinolin-5- yl)urea::US9771359, EX-56

SMILES CC(C)(C)c1nc(c(CNC(=O)Nc2cccc3cnccc23)s1)-c1cccc(Cl)c1

InChI Key InChIKey=MFWMHUIIVYTFQJ-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 342149   

TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Medifron Dbt

US Patent
LigandPNGBDBM342149(1-((2-(tert-butyl)-4-(3-chlorophenyl)thiazol-5-yl)...)
Affinity DataKi:  0.100nMAssay Description:The FLIPR protocol consists of 2 substance additions during a kinetic measurement. First the compounds to be tested (5 μM) are pipetted onto the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent