BDBM344062 US9777017, Example 46::US9908895, Example 46

SMILES CC(=N)C(=C1/NC=Nc2ccsc12)\c1ccc(CC#N)cc1

InChI Key InChIKey=IIJAJMZKGUVZOJ-LIZTXNRTSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 344062   

TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Incyte Holdings

US Patent
LigandPNGBDBM344062(US9777017, Example 46 | US9908895, Example 46)
Affinity DataIC50: <100nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM344062(US9777017, Example 46 | US9908895, Example 46)
Affinity DataIC50: <1.00E+3nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Incyte Holdings

US Patent
LigandPNGBDBM344062(US9777017, Example 46 | US9908895, Example 46)
Affinity DataIC50: <100nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM344062(US9777017, Example 46 | US9908895, Example 46)
Affinity DataIC50: <1.00E+3nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent