BDBM344397 (E)-N1-(2-fluorophenyl)-N4-(3-fluoro-4-(6-methoxy-7-(3-(piperidin-1-yl)propoxy)quinoline-4-yloxy)benzaldehyde)semicarbazone::US9783499, Example 47

SMILES COc1cc2c(Oc3ccc(\C=N\N(C(N)=O)c4ccccc4F)cc3F)ccnc2cc1OCCCN1CCCCC1

InChI Key InChIKey=GJLAAJORZQLVMD-FDALDRLYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 344397   

TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Shenyang Pharmaceutical University

US Patent
LigandPNGBDBM344397((E)-N1-(2-fluorophenyl)-N4-(3-fluoro-4-(6-methoxy-...)
Affinity DataIC50:  21nMAssay Description:c-Met Kinase Activity was Measured with an ELISA Reader. The Specific Operation as Follows:To the plate filled with 0.25 mg/mL PGT, the compounds, 50...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent