BDBM344401 (E)-N1-(4-chlorophenyl)-N4-(3-fluoro-4-(6-methoxy-7-(3-(4-methyl-1-piperazinyl)propoxy)quinoline-4-yloxy)benzaldehyde)semicarbazone::US9783499, Example 53

SMILES COc1cc2c(Oc3ccc(\C=N\N(C(N)=O)c4ccc(Cl)cc4)cc3F)ccnc2cc1OCCCN1CCN(C)CC1

InChI Key InChIKey=ZBNWNMKHAOONGE-FDALDRLYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 344401   

TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Shenyang Pharmaceutical University

US Patent
LigandPNGBDBM344401((E)-N1-(4-chlorophenyl)-N4-(3-fluoro-4-(6-methoxy-...)
Affinity DataIC50:  580nMAssay Description:c-Met Kinase Activity was Measured with an ELISA Reader. The Specific Operation as Follows:To the plate filled with 0.25 mg/mL PGT, the compounds, 50...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent