BDBM345147 3-Methoxy-N-((2S,3R,4R,5R)-2,3,4,5,6-pentahydroxyhexyl)-5-((4-((4-(3-(1-(p-tolyl)-3-(trimethylsilyl)-1H-pyrazol-5-yl)ureido)naphthalen-1-yl)oxy)pyrimidin-2-yl)amino)-benzamide::US9783556, Example 19

SMILES COc1cc(Nc2nccc(Oc3ccc(NC(=O)Nc4cc(nn4-c4ccc(C)cc4)[Si](C)(C)C)c4ccccc34)n2)cc(c1)C(=O)NC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO

InChI Key InChIKey=WPSMIJIJTXKTLJ-QIPNZGSESA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 345147   

TargetGlycogen synthase kinase-3 alpha(Homo sapiens (Human))
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US Patent
LigandPNGBDBM345147(3-Methoxy-N-((2S,3R,4R,5R)-2,3,4,5,6-pentahydroxyh...)
Affinity DataIC50:  370nMAssay Description:The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent