BDBM345568 Butane-1-sulfonic acid [2-(2-fluoro- 6-methyl-phenoxy)-6-(1-methyl-6- oxo-1,6-dihydro-pyridin-3-yl)- pyrimidin-4-yl]-amide::US10202360, Example 113
SMILES CCCCS(=O)(=O)Nc1cc(nc(Oc2c(C)cccc2F)n1)-c1ccc(=O)n(C)c1
InChI Key InChIKey=KIUXMESFQFPSQB-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 345568
Affinity DataIC50: <500nMAssay Description:Determination of the IC50 for the CREBBP inhibitors disclosed herein was performed as follows: CREBBP was cloned and expressed in E. Coli as His-tag ...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 4 [42-168](Homo sapiens (Human))
Celgene Quanticel Research
US Patent
Celgene Quanticel Research
US Patent
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of BRD4 was determined as previously described in U.S. Pat. No. 9,034,900.More data for this Ligand-Target Pair
Affinity DataIC50: <500nMAssay Description:Determination of the IC50 for the CREBBP inhibitors disclosed herein was performed as follows: CREBBP was cloned and expressed in E. Coli as His-tag ...More data for this Ligand-Target Pair