BDBM345577 Butane-1-sulfonic acid [6-(5-chloro- 1-methyl-6-oxo-1,6-dihydro- pyridin-3-yl)-2-(2-fluoro-6-methyl- phenoxy)-pyrimidin-4-yl]-amide::US10202360, Example 122

SMILES CCCCS(=O)(=O)Nc1cc(nc(Oc2c(C)cccc2F)n1)-c1cc(Cl)c(=O)n(C)c1

InChI Key InChIKey=IIWJHSMXQJFTNG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 345577   

TargetCREB-binding protein(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM345577(Butane-1-sulfonic acid [6-(5-chloro- 1-methyl-6-ox...)
Affinity DataIC50: <500nMAssay Description:Determination of the IC50 for the CREBBP inhibitors disclosed herein was performed as follows: CREBBP was cloned and expressed in E. Coli as His-tag ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent