BDBM345587 5-[2-(2,4-Difluoro-phenoxy)-6- methanesulfonyl-pyrimidin-4-yl]- 1,3-dimethyl-1H-pyridin-2-one::US10202360, Example 132

SMILES Cc1cc(cn(C)c1=O)-c1cc(nc(Oc2ccc(F)cc2F)n1)S(C)(=O)=O

InChI Key InChIKey=LKPNRYQIVWIRLV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 345587   

TargetCREB-binding protein(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM345587(5-[2-(2,4-Difluoro-phenoxy)-6- methanesulfonyl-pyr...)
Affinity DataIC50: <500nMAssay Description:Determination of the IC50 for the CREBBP inhibitors disclosed herein was performed as follows: CREBBP was cloned and expressed in E. Coli as His-tag ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent