BDBM345606 N-(6-(1,5-dimethyl-6-oxo-1,6- dihydropyridin-3-yl)-2-(2,2,2- trifluoroethoxy)pyrimidin-4- yl)ethanesulfonamide::US10202360, Example 151

SMILES CCS(=O)(=O)Nc1cc(nc(OCC(F)(F)F)n1)-c1cc(C)c(=O)n(C)c1

InChI Key InChIKey=DHUOUQLVJKEDBF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 345606   

TargetCREB-binding protein(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM345606(N-(6-(1,5-dimethyl-6-oxo-1,6- dihydropyridin-3-yl)...)
Affinity DataIC50: <500nMAssay Description:Determination of the IC50 for the CREBBP inhibitors disclosed herein was performed as follows: CREBBP was cloned and expressed in E. Coli as His-tag ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent