BDBM346277 US10202377, Compound 46
SMILES Fc1ccc(cc1)-c1cccc2[nH]c(nc12)-c1n[nH]c2cnc(cc12)-c1cncc(NC(=O)C2CCC2)c1
InChI Key InChIKey=OERSZKKSURKBEU-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 346277
Affinity DataEC50: 94nMAssay Description:Compound Screening: Each compound was dissolved in DMSO as a 10 mM stock and used to prepare compound source plates. Serial dilution (1:2, 11-point d...More data for this Ligand-Target Pair
Affinity DataIC50: 48.9nMAssay Description:The screening assay for Wnt activity is described as follows. Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., col...More data for this Ligand-Target Pair