BDBM346484 3-(5-isopropyl-1,3,4-oxadiazol-2-yl)-2,6-dimethyl-4-(4,4,4-trifluoro-3-hydroxy-3-phenyl-but-1-ynyl)-1H-pyrrolo[2,3-c]pyridin-7-one::US10202378, Example 189::US10202378, Example 94a::US10202378, Example 94b
SMILES CC(C)c1nnc(o1)-c1c(C)[nH]c2c1c(cn(C)c2=O)C#CC(O)(c1ccccc1)C(F)(F)F
InChI Key
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 346484
TargetTranscription initiation factor TFIID subunit 1 [1504-1635](Homo sapiens (Human))
Genentech
US Patent
Genentech
US Patent
Affinity DataIC50: 49.5nMAssay Description:His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...More data for this Ligand-Target Pair
TargetTranscription initiation factor TFIID subunit 1 [1381-1497](Homo sapiens (human))
Genentech
US Patent
Genentech
US Patent
Affinity DataIC50: 492nMAssay Description:His/Flag epitope tagged TAF1-BD11381-1497 was cloned, expressed, and purified to homogeneity. TAF1-BD binding and inhibition was assessed by monitori...More data for this Ligand-Target Pair
TargetTranscription initiation factor TFIID subunit 1 [1381-1497](Homo sapiens (human))
Genentech
US Patent
Genentech
US Patent
Affinity DataIC50: 949nMAssay Description:His/Flag epitope tagged TAF1-BD11381-1497 was cloned, expressed, and purified to homogeneity. TAF1-BD binding and inhibition was assessed by monitori...More data for this Ligand-Target Pair
TargetTranscription initiation factor TFIID subunit 1 [1381-1497](Homo sapiens (human))
Genentech
US Patent
Genentech
US Patent
Affinity DataIC50: 192nMAssay Description:His/Flag epitope tagged TAF1-BD11381-1497 was cloned, expressed, and purified to homogeneity. TAF1-BD binding and inhibition was assessed by monitori...More data for this Ligand-Target Pair
TargetTranscription initiation factor TFIID subunit 1 [1504-1635](Homo sapiens (Human))
Genentech
US Patent
Genentech
US Patent
Affinity DataIC50: 126nMAssay Description:His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...More data for this Ligand-Target Pair
TargetTranscription initiation factor TFIID subunit 1 [1504-1635](Homo sapiens (Human))
Genentech
US Patent
Genentech
US Patent
Affinity DataIC50: 27.6nMAssay Description:His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...More data for this Ligand-Target Pair