BDBM348915 4-(2- (cyclopropanecarboxamido)- [1,2,4]triazolo[1,5-a]pyridin-5- yl)-N-(3- fluorobenzyl)benzamide::US10206907, Compound 29
SMILES Fc1cccc(CNC(=O)c2ccc(cc2)-c2cccc3nc(NC(=O)C4CC4)nn23)c1
InChI Key InChIKey=QXPXHVGWDQFSMM-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 348915
Affinity DataIC50: >1.00E+3nMAssay Description:Recombinant human JAK3 catalytic domain (amino acids 781-1124; catalog number PV3855) was purchased from Invitrogen. 0.025 mU of JAK3 was incubated w...More data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Recombinant human JAK2 catalytic domain (amino acids 808-1132; catalog number PV4210) was purchased from Invitrogen. 0.025 mU of JAK2 was incubated w...More data for this Ligand-Target Pair
Affinity DataIC50: <100nMAssay Description:Recombinant human JAK1 catalytic domain (amino acids 850-1154; catalog number 08-144) was purchased from Carna Biosciences. 10 ng of JAK1 was incubat...More data for this Ligand-Target Pair