BDBM350133 US10208047, Example 1

SMILES C[C@@](O)(c1ccc(cc1)-c1nc(n2ccnc(N)c12)C1(C)CCC(C)(CC1)C(O)=O)c1cccc(c1)C(F)(F)F

InChI Key InChIKey=RZRKHFAZESJNSD-BVDFDZHASA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 350133   

TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM350133(US10208047, Example 1)
Affinity DataIC50:  39.4nMAssay Description:BTK enzymatic activity was determined with the LANCE (Lanthanide Chelate Excite) TR-FRET (Time-resolved fluorescence resonance energy transfer) assay...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent