BDBM350160 (1S,3R)-3-[8-amino-1-(2- ethoxy-4-{(1S)-1-hydroxy- 1-[3- (trifluoromethyl)phenyl] ethyl}phenyl)imidazo[1,5- a]pyrazin-3-yl]-1,2,2- trimethylcyclopentane- carboxylic acid::US10208047, Example 28
SMILES CCOc1cc(ccc1-c1nc([C@@H]2CC[C@](C)(C(O)=O)C2(C)C)n2ccnc(N)c12)[C@@](C)(O)c1cccc(c1)C(F)(F)F
InChI Key InChIKey=WONMLGXSOPQUNB-VHCCWIOHSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 350160
Affinity DataIC50: 1.20nMAssay Description:BTK enzymatic activity was determined with the LANCE (Lanthanide Chelate Excite) TR-FRET (Time-resolved fluorescence resonance energy transfer) assay...More data for this Ligand-Target Pair