BDBM350894 2-Ethylthio-3-phenyl-4-oxo-3,4-dihydroquinazoline ::US9796687, Compound 16

SMILES CCSc1nc2ccccc2c(=O)n1-c1ccccc1

InChI Key InChIKey=CFELAOYYJGZQMD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 350894   

TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Homo sapiens (Human))
Instituto De Qu£Mica M£Dica (Csic)

Curated by ChEMBL
LigandPNGBDBM350894(2-Ethylthio-3-phenyl-4-oxo-3,4-dihydroquinazoline ...)
Affinity DataIC50:  6.90E+3nMAssay Description:Inhibition of human recombinant PDE7A1 using [3H]AMP after 20 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Homo sapiens (Human))
Instituto De Qu£Mica M£Dica (Csic)

Curated by ChEMBL
LigandPNGBDBM350894(2-Ethylthio-3-phenyl-4-oxo-3,4-dihydroquinazoline ...)
Affinity DataIC50:  6.90E+3nMAssay Description:Measurement of PDE7 inhibition was carried out using a commercial phosphodiesterase activity measurement kit.Some of the compounds of the present inv...More data for this Ligand-Target Pair
In DepthDetails US Patent